Semiparametric linkage analysis using pseudolikelihoods on neighbouring sets
نویسندگان
چکیده
منابع مشابه
Semiparametric linkage analysis using pseudolikelihoods on neighbouring sets.
For many complex diseases, study has suggested that the disease genes influence not only the occurrence of the disease, but also the age of onset. Current methods in linkage analysis are mainly concentrated on affected relative pairs or affected family members, and age of onset information is either ignored or is taken into account by specifying age-dependent penetrances for liability classes. ...
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ژورنال
عنوان ژورنال: Annals of Human Genetics
سال: 1998
ISSN: 0003-4800,1469-1809
DOI: 10.1046/j.1469-1809.1998.6240323.x